Sarm Gw-501516/Cardarine/GSK-516 for Endurance Incerasing and Fat Loss
|FOB Price:||US $0.75-1 / gram|
|Min. Order:||10 gram|
|Min. Order||FOB Price|
|10 gram||US $0.75-1/ gram|
|Port:||Hong Kong, Hong Kong|
|Payment Terms:||T/T, Western Union, Money Gram, Bitcoin|
- Model NO.: CAS: 317318-70-0
- Customized: Customized
- Suitable for: Elderly, Adult
- Purity: >99%
- Shipping Ways: : UPS, TNT, EMS, DHL, FedEx, etc(Door-to-Door)
- Shipping Time: 3-5 Working Days
- Appearance: White Powder
- Transport Package: as Your Request
- Origin: China
- Powder: Yes
- Certification: ISO 9001, USP, BP
- State: Solid
- Assay: 99% Min.
- Payment Ways: T/T, Western Union, Money Gram, Bitcoin
- Delivery Time: Within 24 Hours After Payment
- Trademark: Chuangshu
- Specification: Qualified
- HS Code: 4400341001
Alias:2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid; GW1516; GW501516; GSK-516
Usage: It had been investigated as a potential treatment for obesity, diabetes, dyslipidemia and cardiovascular disease. GW501516 could be used by athletes as an ergogenic performance enhancing drug.
GW501516 is the most selective and potent PPARβ (EC50=1.1nM) agonist that has been demonstrated to be 1,000-fold more selective in comparison to existing subtypes.
Studies demonstrate that GW501516 can regulate expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells. Additionally, GW501516 has been shown to block insulin resistance and fatty acid-induced nuclear factor-κB (NF-κB) activation.
1.GW501516 (GW1516 or GSK-516) is a drug that acts as a PPARδ modulator. GW 501516 activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue, and GW 501516 has been demonstrated to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation.
2.It has been proposed as a potential treatment for obesity and related conditions, especially when used in conjunction with a synergistic compound AICAR, as the combination has been shown to significantly increase exercise endurance in animal studies.
3.GW50156 regulates fat burning through a number of mechanisms. It increases glucose uptake in skeletal muscle tissue and increases muscle gene expression, especially genes involved in preferential lipid utilization.
4.This shift changes the body's metabolism to favor burning fat for energy instead of carbohydrates or muscle protein, potentially allowing clinical application for obese patients to lose fat effectively without experiencing muscle catabolism or the effects and satiety issues associated with low blood sugar.
5.GW-501516 also increases muscle mass, which improved glucose tolerance and reduced fat mass accumulation even in mice fed a very high fat diet, suggesting that GW-501516 may have a protective effect against obesity.
GW-501516 is often used in two aspects. The first and most common use is that of increased endurance. GW has been banned for professional athletes due to the unfair advantage it provides to endurance athletes. Anyone want a drastic increase in endurance will find that GW truly shines in this aspect. It takes effect very quickly and the results can be staggering. A common dose of 10 mg day will provide a significant increase in endurance.
The second one is that of fat burning. Many users turn to GW as it has shown to melt off fat while still being non-catabolic. You will find that you can still hold on to some muscle as you are losing fat. It helps when you are running it in conjunction with SARMS Ostarine and S4, to hold on to as much muscle as possible. A dosage of 10 mg a day will provide good amounts of fat loss, but an increase to 20 mg a day will provide much more in this area.
|SARMS Powder||CAS NO.|