Gold Member Since 2016
Wuhan Chuangshu E-Commerce Co., Ltd.

Propofol, Pure Propofol, Liquid Propofol manufacturer / supplier in China, offering 99% Pure Colorless Liquid Propofol for General Anesthesia, Cosmetic Anti-Wrinkle Peptide 99% Purity Acetyl Octapeptide-3 Snap-8 CAS 868844-74-0, Testosterone Suspension Water-Based Liquid for Gain Muscle Fat Loss and so on.

(/ )

Supplier Homepage Product Pharmaceutical Raw Material Local Anesthesia Drug 99% Pure Colorless Liquid Propofol for General Anesthesia

99% Pure Colorless Liquid Propofol for General Anesthesia

FOB Price: US $1 / g
Min. Order: 1 g
Min. Order FOB Price
1 g US $1/ g
Get Latest Price
Port: Hong Kong, Hong Kong
Production Capacity: 1000kgs/Month
Payment Terms: T/T, Western Union, Money Gram, Bitcoin

Request a custom order and have something just for you!

Send Customized Request
Basic Info
  • Powder: Yes
  • Certification: ISO 9001, USP
  • State: Solid
  • Usage: Local Anesthetic Benzocaine
  • Payment Ways: T/T, Western Union, Moneygram, Bitcoin
  • Shipping Time: Within 24 Hours
  • Trademark: Chuangshu
  • Specification: 30g
  • HS Code: 9006956326
  • Customized: Customized
  • Suitable for: Elderly, Adult
  • Purity: >99%
  • Grade: USP
  • Shipping Ways: EMS, DHL, FedEx, etc(Door-to-Door)
  • Delivery Time: 4-7 Working Days
  • Transport Package: According to Customer′s Demand
  • Origin: China
Product Description
Product Description
 
Anesthesia
Propofol is used for induction and maintenance (in some cases) of anesthesia, having largely replaced sodium thiopental. It can also be administered as part of an anaesthesia maintenance technique called total intravenous anesthesia using either manually-programmed infusion pumps or computer-controlled infusion pumps in a process called target controlled infusion or TCI. Propofol is also used to sedate individuals who are receiving mechanical ventilation but are not undergoing surgery, such as patients in theintensive care unit. In critically ill patients, propofol has been found to be superior to lorazepam both in effectiveness and overall cost.
Propofol is often used instead of sodium thiopental for starting anesthesia because recovery from propofol is more rapid and "clear."
Procedural sedation
Propofol is also used for procedural sedation. Its use in these settings results in a faster recovery compared to midazolam. It can also be combined with opioids or benzodiazepines. Because of its fast induction and recovery time, propofol is also widely used for sedation of infants and children undergoing MRI. It is also often used in combination with ketamine as the two together have lower rates of side effects.
 
General
DIPRIVAN Injectable Emulsion is an intravenous sedative-hypnotic agent for use in the induction and maintenance of anesthesia or sedation. Intravenous injection of a therapeutic dose of propofol induces hypnosis, with minimal excitation, usually within 40 seconds from the start of injection (the time for one arm-brain circulation). As with other rapidly acting intravenous anestheticagents, the half-time of the blood-brain equilibration is approximately 1 to 3 minutes, accounting for the rate of induction of anesthesia. The mechanism of action, like all general anesthetics, is poorly understood. However, propofol is thought to produce its sedative/anesthetic effects by the positive modulation of the inhibitory function of the neurotransmitter GABA through the ligand-gated GABAa receptors.
Pharmacodynamics
Pharmacodynamic properties of propofol are dependent upon the therapeutic blood propofol concentrations. Steady-state propofol blood concentrations are generally proportional to infusion rates. Undesirable side effects, such as cardiorespiratory depression, are likely to occur at higher blood concentrations which result from bolus dosing or rapid increases in infusion rates. An adequate interval (3 to 5 minutes) must be allowed between dose adjustments in order to assess clinical effects.
The hemodynamic effects of DIPRIVAN Injectable Emulsion during induction of anesthesia vary. If spontaneous ventilation is maintained, the majorcardiovascular effect is arterial hypotension (sometimes greater than a 30% decrease) with little or no change in heart rate and no appreciable decrease in cardiac output. If ventilation is assisted or controlled (positive pressure ventilation), there is an increase in the incidence and the degree of depression of cardiac output. Addition of an opioid, used as a premedicant, further decreases cardiac output and respiratory drive.
If anesthesia is continued by infusion of DIPRIVAN Injectable Emulsion, the stimulation of endotracheal intubation and surgery may return arterial pressure towards normal. However, cardiac output may remain depressed. Comparative clinical studies have shown that the hemodynamic effects of DIPRIVAN Injectable Emulsion during induction of anesthesia are generally more pronounced than with other intravenous (IV) induction agents.
Induction of anesthesia with DIPRIVAN Injectable Emulsion is frequently associated with apnea in both adults and pediatric patients. In adult patients who received DIPRIVAN Injectable Emulsion (2 to 2.5 mg/kg), apnea lasted less than 30 seconds in 7% of patients, 30 to 60 seconds in 24% of patients, and more than 60 seconds in 12% of patients. In pediatric patients from birth through 16 years of age assessable for apnea who received bolus doses of DIPRIVAN Injectable Emulsion (1 to 3.6 mg/kg), apnea lasted less than 30 seconds in 12% of patients, 30 to 60 seconds in 10% of patients, and more than 60 seconds in 5% of patients.
During maintenance of general anesthesia, DIPRIVAN Injectable Emulsion causes a decrease in spontaneous minute ventilation usually associated with an increase in carbon dioxide tension which may be marked depending upon the rate of administration and concurrent use of other medications (e.g., opioids, sedatives, etc.).
During monitored anesthesia care (MAC) sedation, attention must be given to the cardiorespiratory effects of DIPRIVAN Injectable Emulsion. Hypotension,oxyhemoglobin desaturation, apnea, and airway obstruction can occur, especially following a rapid bolus of DIPRIVAN Injectable Emulsion. During initiation of MAC sedation, slow infusion or slow injection techniques are preferable over rapid bolus administration. During maintenance of MAC sedation, a variable rate infusion is preferable over intermittent bolus administration in order to minimize undesirable cardiorespiratory effects. In the elderly, debilitated, or ASAPS III or IV patients, rapid (single or repeated) bolus dose administration should not be used for MAC sedation 
Clinical and preclinical studies suggest that DIPRIVAN Injectable Emulsion is rarely associated with elevation of plasma histamine levels.
Preliminary findings in patients with normal intraocular pressure indicate that DIPRIVAN Injectable Emulsion produces a decrease in intraocular pressurewhich may be associated with a concomitant decrease in systemic vascularresistance.
Clinical studies indicate that DIPRIVAN Injectable Emulsion when used in combination with hypocarbia increases cerebrovascular resistance and decreases cerebral blood flow, cerebral metabolic oxygen consumption, andintracranial pressure. DIPRIVAN Injectable Emulsion does not affect cerebrovascular reactivity to changes in arterial carbon dioxide tension (seeClinical Trials, Neuroanesthesia).
Clinical studies indicate that DIPRIVAN Injectable Emulsion does not suppress the adrenal response to ACTH.
Animal studies and limited experience in susceptible patients have not indicated any propensity of DIPRIVAN Injectable Emulsion to inducemalignant hyperthermia.
Hemosiderin deposits have been observed in the livers of dogs receiving DIPRIVAN Injectable Emulsion containing 0.005% disodium edetate over a four-week period; the clinical significance of this is unknown.
Pharmacokinetics
The pharmacokinetics of propofol are well described by a three compartment linear model with compartments representing the plasma, rapidly equilibrating tissues, and slowly equilibrating tissues.
Following an IV bolus dose, there is rapid equilibration between the plasma and the brain, accounting for the rapid onset of anesthesia. Plasma levels initially decline rapidly as a result of both distribution and metabolic clearance. Distribution accounts for about half of this decline following a bolus of propofol. However, distribution is not constant over time, but decreases as body tissues equilibrate with plasma and become saturated. The rate at which equilibration occurs is a function of the rate and duration of the infusion. When equilibration occurs there is no longer a net transfer of propofol between tissues and plasma.
Discontinuation of the recommended doses of DIPRIVAN Injectable Emulsion after the maintenance of anesthesia for approximately one hour, or for sedation in the ICU for one day, results in a prompt decrease in blood propofol concentrations and rapid awakening. Longer infusions (10 days of ICU sedation) result in accumulation of significant tissue stores of propofol, such that the reduction in circulating propofol is slowed and the time to awakening is increased.
By daily titration of DIPRIVAN Injectable Emulsion dosage to achieve only the minimum effective therapeutic concentration, rapid awakening within 10 to 15 minutes can occur even after long-term administration. If, however, higher than necessary infusion levels have been maintained for a long time, propofol redistribution from fat and muscle to the plasma can be significant and slow recovery.
The figure below illustrates the fall of plasma propofol levels following infusions of various durations to provide ICU sedation.

Related hot selling  Anesthetic APIs
NameCAS#
local anaesthetics APLS 
BenzocaineCAS:94-09-7
Benzocaine hydrochlorideCAS: 23239-88-5
Lidocaine BaseCAS:137-58-6
Lidocaine HydrochlorideCAS:73-78-9
Procaine hydrochlorideCAS:51-05-8
Tetracaine hydrochlorideCAS:136-47-0
Articaine hydrochlorideCAS:23964-57-0
Propitocaine hydrochlorideCAS:1786-81-8
Levobupivacaine hydrochlorideCAS:27262-48-2
Proparacaine hydrochlorideCAS: 5875-06-9 
Ropivacaine hydrochlorideCAS: 132112-35-7 
Ropivacaine mesylateCAS:854056-07-8
Bupivacaine hydrochlorideCAS: 14252-80-3 
DibucaineCAS:85-79-0
PrilocaineCAS:721-50-6
ProparacaineCAS:298-50-0
ArticaineCAS:23964-58-1
Bupivacaine CAS:2180-92-9


 
   
We also supply:
 
CZG

Popular Steroid
 
1Testosterone EnanthateCAS: 315-37-7 
2Testosterone AcetateCAS: 1045-69-8 
3Testosterone PropionateCAS: 57-85-2 
4Testosterone CypionateCAS: 58-20-8 
5Testosterone PhenylpropionateCAS: 1255-49-8 
6Testosterone IsocaproateCAS: 15262-86-9 
7Testosterone DecanoateCAS: 5721-91-5 
8Testosterone UndecanoateCAS: 5949-44-0 
9Sustanon 250  
101-Testosterone Cypionate  
11TurinabolCAS: 855-19-6 
12Oral TurinabolCAS: 2446-23-3 
13StanoloneCAS: 521-18-6 
14Nandrolone Decanoate (DECA)CAS: 360-70-3 
15Nandrolone Cypionate CAS: 601-63-8 
16Nandrolone Phenypropionate (NPP)CAS: 62-90-8 
17Boldenone AcetateCAS :2363-59-9 
18Boldenone Undecylenate (Equipoise) CAS: 13103-34-9 
19Drostanolone Propionate (Masteron) CAS: 521-12-0 
20Drostanolone Enanthate CAS: 472-61-1 
21Methenolone Acetate (Primobolan)CAS: 434-05-9 
22Methenolone Enanthate CAS: 303-42-4 
23Trenbolone AcetateCAS: 10161-34-9 
24Trenbolone Enanthate   
25Trenbolone Hexahydrobenzyl CarbonateCAS: 23454-33-3 
26Epiandrosterone CAS: 481-29-8 
 
Oral Steroid
 
27AnavarCAS: 53-39-4 
28AnadrolCAS: 434-07-1 
29WinstrolCAS: 10418-03-8 
30DianabolCAS: 72-63-9 
31SuperdrolCAS: 3381-88-2 
 
Anti-Estrogen
32Tamoxifen Citrate (Nolvadex) CAS: 54965-24-1 
33Clomiphene Citrate (Clomid)CAS: 50-41-9 
34Toremifene Citrate (Fareston)CAS: 89778-27-8 
35FemaraCAS: 112809-51-5 
36AromasinCAS: 107868-30-4 
37ProvironCAS: 1424-00-6 
38ArimidexCAS: 120511-73-1 
39 CAS: 566-48-3 
40Cabergoline (Caber)CAS: 81409-90-7 
41FinasterideCAS: 98319-26-7 
42Dutasteride CAS: 164656-23-9 
 
SARM
 
43Ostarine (MK-2866)CAS: 841205-47-8 
44Cardarine (GW-501516)CAS: 317318-70-0 
45Andarine (S4)CAS: 401900-40-1 
46Ligandrol (LGD-4033)CAS: 1165910-22-4 
47Ibutamoren (MK-677)CAS: 159752-10-0 
48RAD140CAS: 118237-47-0 
49SR9009CAS: 1379686-30-2 
50YK11CAS: 431579-34-9 
 
Sex Enhancement
 
51AvanafilCAS: 330784-47-9 
52VardenafilCAS: 224785-91-5 
53DapoxetineCAS: 119356-77-3 
54TadalafilCAS: 171596-29-5 
55     
56Vardenafil HydrochlorideCAS: 431579-34-9 
57Dapoxetine HydrochlorideCAS: 431579-34-9 
58Yohimbine HydrochlorideCAS: 65-19-0 
 
Pharmaceutical Intermediate
 
59T3CAS: 55-06-1 
60T4CAS: 51-48-9 
61Ethyl Oleate(EO)CAS: 111-62-6 
62Benzyl Alcohol (BA)CAS: 100-51-6 
63Benzyl Benzoate (BB)CAS: 120-51-4 
64Grape Seed Oil (GSO)CAS: 85594-37-2 
65   
661,3-Dimethylpentylamine (DMAA)CAS: 13803-74-2 
674-Acetamidophenol (Paracetamol)CAS:103-90-2 
68Tauroursodeoxycholic Acid (TUDCA)CAS: 14605-22-2 
69Dextromethorphan Hydrobromide (DXM)CAS: 6700-34-1 
 
 
 
 
 Injection Steroid liquid 
 
Test Series
Test Base 100mg/ml @100ml
Testosterone Cypionate 250mg/ml @100ml 
Testosterone Enathate  250mg/ml @100ml 
Testosterone Enathate  600mg/ml @100ml 
Testosterone Propionate 100mg/ml @100ml
Testosterone Propionate 200mg/ml @100ml
Testosterone Undecanoate 500mg/ml @100ml 
Testosterone Sustanon 200mg/ml @100ml
Testosterone Sustanon 250mg/ml @100ml
Testosterone Sustanon 300mg/ml @100ml
Testosterone Sustanon 400mg/ml @100ml
Turinabol 50mg/ml @ 200ml
 
Bold  Series
Boldenone Undecylenate 300mg/ml @100ml
Boldenone Cypionate 200mg/ml @100ml 
 
Nand  Series 
Nandrolone Decanoate 200mg/ml @100ml
Nandrolone Decanoate 250mg/ml @100ml
Nandrolone cypionate 200mg/ml @100ml 
Nandrolone phenylpropionate 200mg/ml @100ml
 
Tren  Series
Tren base 100mg/ml @100ml
Tren Acetate 80mg/ml @100ml
Tren Acetate 100mg/ml @100ml
Tren Acetate 200mg/ml @100ml
Tren Enanthate 60mg/ml @100ml
Tren Enanthate 100mg/ml @100ml
Tren Enanthate 150mg/ml @100ml
Tren  Enanthate 200mg/ml @100ml
Parabolone (Trenb Hexahydrobenzyl Carbonate ) 50mg/ml @100ml
Parabolone (Trenb Hexahydrobenzyl Carbonate ) 75mg/ml @100ml
 
Series 
Drostanolone Propionate 100mg/ml @100ml
Drostanolone Enanthate  200mg/ml @100ml
 
Methenolon  Series
Primobolan (Methenolon Enanthate)    100mg/ml@ 100ml 
 
Other injections 
Stanozol(Winstrol) 100mg/ml @100ml
Oxymetholon (Anadrol) 50mg/ml @100ml
Oxandrolon(Anavar)   50mg/ml @100ml
 
Oral liquid
Stanozolo (Winstrol) 25mg/ml @100ml
Oxymetholon (Anadrol) 50mg/ml @100ml
Oxandrolon (Anavar)   20mg/ml @100ml
Clomid(Clomiphen citrate) 50mg/ml @100ml
Nolvadex(TamoxifCitrate) 20mg/ml @100ml
Arimidex (Anastrozol) 5mg/ml @500ml
Femara(Letrozol) 5mg/ml @500ml
Proviron(Mesterolon) 50mg/ml @100ml 
Blend steroid solutions
Supertest 450 (Testosterone acetate 32mg
Testosterone decanoate 147mg
Testosterone propionate 73mg
Testosterone phenylpropionate 73mg
Testosterone cypionate 125mg) @100ml
Anomass 400mg (Testosterone Enathate 150mg 
Boldenone Undeclynate 150mg              
Tren Enanthate 100mg) @100ml
Ripex225(Testosterone Propionate 75 mg 
Tren Acetate 75 mg 
Drostanolone Propionate 75 mg) @100ml
TriTren 180 (tren acetate 60mg       
tren Enanthate 60mg 
tren hexahydrobenzyl carbonate 60mg ) @100ml
Tri Test 300(Testosterone decanoate 100mg 
Testosterone Isocaproate 50mg 
Testosterone Phenylpropionate 100mg 
Testosterone propionate 50mg ) @100ml 
Tri Deca 300(nandrolone decanoate 150mg 
nandrolone phenylpropionate 75mg 
nandrolone undecanoate 75mg ) @100ml
TMT Blend 375(Tren Enanthate 125mg/ml 
Drostanolone Enanthate 125mg/ml 
Testosterone Enanthate 125mg/ml) @100ml
TM Blend 500(Tren Enanthate 250mg/ml 
Drostanolone Enanthate 250mg/ml) @100ml 

 
 
FAQ:
How to make steroids liquid at home?
How to make steroids tablets at home?
How to make steroids pills at home?
 
 
Our 3 Guaranteed:
 
1,Quality Guaranteed :
Most of our powder with USP grade and all with high purity
 
2,Shipping Time Guaranteed:
we can send out parcel within 12- 24 hours after receiving your payment, and shipping way according to customer demand
 
3,Delivery Guaranteed:
a:We take discreet package
b:We will recommend the safest shipping way according to your country
C:We will try best to keep parcel safe, and also Warranty ,resending police if the tracking number do not update online or it sezied by custom
 
Send your message to this supplier
Avatar
Miss Emma
Email: Roidsupply@Chembj. Com
*From:
To: Miss Emma
*Message:

Enter between 20 to 4,000 characters.

This is not what you are looking for? Post a Sourcing Request Now

Find Similar Products By Category